SCHEMBL3617428

SCHEMBL3617428

O=c1ccoc2c1ccc1ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
KDM4E B2RXH2 5/20 0.54
HTT P42858 4/20 0.54
KMT2A Q03164 3/20 0.54
POLB P06746 2/20 0.54
ESR1 P03372 1/20 0.54
MAPT P10636 4/20 0.53
PAX8 Q06710 2/20 0.53
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
FTO Q9C0B1 1/20 0.52
CYP1A1 P04798 7/20 0.50
CYP1B1 Q16678 7/20 0.50
CYP1A2 P05177 6/20 0.50
HPGD P15428 5/20 0.50
MEN1 O00255 2/20 0.50
HSD17B10 Q99714 2/20 0.50
PRKDC P78527 2/20 0.50
LMNA P02545 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29627465 1.00 ALDH1A1 (0.54) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL29025751 0.93 PAX8 (0.57) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL3584109 0.79 ALDH1A1 (0.49) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL8563087 0.77 ALDH1A1 (0.50) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL29853219 0.77 ALDH1A1 (0.50) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL28174357 0.75 ALDH1A1 (0.55) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL28763218 0.74 HPRT1 (0.44) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL31360532 0.74 HPRT1 (0.44) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL11350264 0.74 LMNA (0.47) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL13167563 0.73 CYP1A1 (0.43) ALDH1A1KDM4EHTTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3807264-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2021-04-21 EP claimed
WO-2019238786-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2019-12-19 WO claimed
CN-114560837-B Chromone compound and preparation method and application thereof 五邑大学 2023-11-24 CN disclosed
US-11467158-B2 BRCA1 mutations as predictive markers for topoisomerase inhibitions BOSTON MEDICAL CENTER CORPORATION (US) 2022-10-11 US disclosed
CN-114560837-A Chromone compound and preparation method and application thereof 五邑大学 2022-05-31 CN disclosed
CN-113105468-B Polycyclic spiroindolone compound containing benzopyrone and preparation method and application thereof 广州大学 2022-03-22 CN disclosed
EP-3807264-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2021-04-21 EP disclosed
WO-2019238786-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2019-12-19 WO disclosed
US-9459533-B2 Polymer composition, photoresist comprising the polymer composition, and coated article comprising the photoresist DOW GLOBAL TECHNOLOGIES LLC (US) 2016-10-04 US disclosed
US-8936900-B2 Calixarene and photoresist composition comprising same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2015-01-20 US disclosed
US-8765356-B2 Calixarene compound and photoresist composition comprising same DOW GLOBAL TECHNOLOGIES LLC (US) 2014-07-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
US-5770382-A RETINOIC ACID AND RETINOID X RECEPTOR AGONISTS; TREATINGSKIN, EYE, BRAIN, AND CARDIOVASCULAR DISORDERS; CANCER LIGAND PHARMACEUTICALS, INC. (US) 1998-06-23 US disclosed
US-5770378-A A VITAMINE A METABOLITE, POTENT DRUGS TREATING SKIN DISEASES, CANCER, EYE DISEASES, CARDIOVASCULAR DISORDERS LIGAND PHARMACEUTICALS, INC. (US) 1998-06-23 US disclosed
US-5770383-A ACTIVATE RETINOID RECEPTORS LIGAND PHARMACEUTICALS, INC. (US) 1998-06-23 US disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed