Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1598557 | 1.00 | LPL (0.47) | LPLLIPGCYP4F2CYP4A11TP53 | |
| SCHEMBL6224542 | 0.92 | TP53 (0.49) | LPLLIPGTP53POLBHPGD | |
| SCHEMBL14746472 | 0.85 | CA12 (0.49) | LPLLIPGTP53CA12CA1 | |
| SCHEMBL22866678 | 0.85 | ALDH1A1 (0.43) | LPLLIPGALDH1A1TSHR | |
| SCHEMBL2569288 | 0.84 | TDP1 (0.54) | LPLLIPGPOLBHPGDALDH1A1 | |
| SCHEMBL29535925 | 0.84 | LOXL2 (0.45) | LPLLIPGCYP4F2CYP4A11TP53 | |
| SCHEMBL1902494 | 0.84 | LOXL2 (0.45) | LPLLIPGCYP4F2CYP4A11TP53 | |
| SCHEMBL29187942 | 0.83 | P4HB (0.40) | LPLLIPGCYP4F2CYP4A11TP53 | |
| SCHEMBL3686298 | 0.82 | CA1 (0.53) | LPLLIPGHPGDCA12CA1 | |
| SCHEMBL20288117 | 0.81 | LIPG (0.50) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997096-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2022-05-18 | — | — | EP | disclosed |