SCHEMBL29628445

SCHEMBL29628445

C=Cc1cc(Cl)c(Cl)cn1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11453867 0.80 AHR (0.31) S1PR4
SCHEMBL12301889 0.80 CD44 (0.32) S1PR4ALDH1A1
SCHEMBL21262514 0.80 GAA (0.39) S1PR4
SCHEMBL29210595 0.76 ALDH1A1 (0.38) S1PR4ALDH1A1
SCHEMBL29628323 0.76
SCHEMBL29628508 0.76 NOTUM (0.34) S1PR4ALDH1A1
SCHEMBL22270470 0.74 NNMT (0.33) S1PR4
SCHEMBL17893893 0.73 POLB (0.37) S1PR4ALDH1A1
SCHEMBL20402506 0.72 ALDH1A3 (0.42) ALDH1A1
SCHEMBL27238773 0.72 LMNA (0.37) S1PR4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3997096-A1 NEW HETEROCYCLIC COMPOUNDS F. Hoffmann-La Roche AG (CH) 2022-05-18 EP disclosed