Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558217 | 0.98 | LMNA (0.47) | LMNASMN1; SMN2MCOLN3PSMB5ESR2 | |
| Hydrogen Sulfide SCHEMBL27610664 | 0.96 | LMNA (0.46) | LMNASMN1; SMN2MCOLN3PSMB5ESR2 | |
| Hydrogen Sulfide SCHEMBL28009940 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2MCOLN3PSMB5ESR2 | |
| SCHEMBL20595542 | 0.86 | PSMB5 (0.40) | LMNASMN1; SMN2MCOLN3PSMB5ESR2 | |
| Hydrogen Sulfide SCHEMBL27971373 | 0.86 | LMNA (0.43) | LMNASMN1; SMN2MCOLN3PSMB5ESR2 | |
| Bromide SCHEMBL20595538 | 0.85 | ENPP3 (0.39) | LMNASMN1; SMN2MCOLN3PSMB5ESR2 | |
| SCHEMBL20595539 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2MCOLN3PSMB5ESR2 | |
| SCHEMBL9695787 | 0.83 | MYC (0.52) | SMN1; SMN2ESR2CA12CA1CA2 | |
| SCHEMBL8038390 | 0.82 | LMNA (0.43) | LMNASMN1; SMN2MCOLN3PSMB5ESR2 | |
| SCHEMBL1133417 | 0.80 | MYC (0.53) | SMN1; SMN2ESR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12297311-B2 | Biaryl hydroxythiophene group IV transition metal polymerization with chain transfer capability | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-05-13 | — | — | US | disclosed |
| US-12122862-B2 | Biaryl hydroxythiophene group IV transition metal polymerization catalysts with chain transfer capability | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-10-22 | — | — | US | disclosed |
| US-20220169756-A1 | BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12122862-B2 | Biaryl hydroxythiophene group IV transition metal polymerization catalysts with chain transfer capability | TRMT1, GFPT1, BCAT1 | LMNA 3683/4885SMN1; SMN2 4058/4885MCOLN3 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.