Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630587 | 0.86 | KDM4E (0.47) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL29630713 | 0.81 | NPC1 (0.55) | L3MBTL1KDM4EALDH1A1CYP19A1CYP11B1 | |
| SCHEMBL30424935 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL27862340 | 0.77 | CA12 (0.44) | ALDH1A1CYP19A1CYP11B1CYP11B2MAPT | |
| SCHEMBL13692247 | 0.71 | SMN1; SMN2 (0.54) | CYP19A1CYP11B1CYP11B2LMNAIDO1 | |
| SCHEMBL3213041 | 0.70 | MIF (0.49) | KDM4EALDH1A1GAAGRIN2BMAPT | |
| SCHEMBL1958148 | 0.70 | KDM4C (0.50) | KDM4EALDH1A1GAAGRIN1GRIN2B | |
| SCHEMBL9747476 | 0.70 | CYP11B1 (0.66) | CYP19A1CYP11B1CYP11B2MAPTPOLB | |
| SCHEMBL440276 | 0.69 | KIF11 (0.50) | L3MBTL1GRIN1GRIN2BRXFP1MRGPRX4 | |
| SCHEMBL29421430 | 0.69 | KIF11 (0.50) | L3MBTL1GRIN1GRIN2BRXFP1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896673-B | Amide derivatives as prostaglandin EP4 receptor antagonists and uses thereof | 安润医药科技（苏州）有限公司 | 2023-05-05 | — | — | CN | disclosed |
| WO-2022111222-A1 | AMIDE DERIVATIVE SERVING AS PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST, AND USE THEREOF | 安润医药科技（苏州）有限公司 | 2022-06-02 | — | — | WO | disclosed |