Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630801 | 0.86 | L3MBTL1 (0.50) | KDM4EALDH1A1GAAKDM4CMAPT | |
| SCHEMBL30424935 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAKDM4CMAPT | |
| SCHEMBL3208460 | 0.72 | TAAR1 (0.55) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL3213041 | 0.70 | MIF (0.49) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL1958148 | 0.70 | KDM4C (0.50) | KDM4EALDH1A1GAAKDM4CMAPT | |
| SCHEMBL9747476 | 0.70 | CYP11B1 (0.66) | MAPTPOLB | |
| SCHEMBL933875 | 0.69 | PTPN1 (0.61) | ALDH1A1ACP3TAAR1MIFIDO1 | |
| SCHEMBL29890941 | 0.69 | PTPN1 (0.61) | ALDH1A1ACP3TAAR1MIFIDO1 | |
| SCHEMBL7193539 | 0.69 | PTPN1 (0.49) | KDM4EALDH1A1GAAKDM4CMAPT | |
| SCHEMBL15707369 | 0.68 | KDM4C (0.56) | KDM4EALDH1A1GAAKDM4CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896673-B | Amide derivatives as prostaglandin EP4 receptor antagonists and uses thereof | 安润医药科技（苏州）有限公司 | 2023-05-05 | — | — | CN | disclosed |
| WO-2022111222-A1 | AMIDE DERIVATIVE SERVING AS PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST, AND USE THEREOF | 安润医药科技（苏州）有限公司 | 2022-06-02 | — | — | WO | disclosed |