Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26125760 | 0.81 | SLC6A7 (0.47) | POLBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL29029905 | 0.80 | GPR119 (0.55) | — | |
| SCHEMBL5368547 | 0.78 | L3MBTL1 (0.49) | POLBKDM4EALDH1A1L3MBTL1GAA | |
| SCHEMBL3539046 | 0.78 | PARP1 (0.44) | POLBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL27233827 | 0.78 | SLC6A7 (0.56) | POLBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL29631883 | 0.78 | KDM4E (0.40) | POLBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL21553750 | 0.76 | POLB (0.45) | POLBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL24467776 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1TSHRHSD17B10CYP2C19 | |
| SCHEMBL3832688 | 0.74 | POLB (0.44) | POLBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL2825734 | 0.74 | PANK3 (0.52) | POLBKDM4EALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |