SCHEMBL29633164

SCHEMBL29633164

CC(C)(C)OC(=O)N(C=N)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.50
NR4A1 P22736 1/20 0.49
NR4A2 P43354 1/20 0.49
NR4A3 Q92570 1/20 0.49
NOX1 Q9Y5S8 2/20 0.47
PARP10 Q53GL7 1/20 0.47
EGFR P00533 3/20 0.46
PPARG P37231 2/20 0.46
ALOX5 P09917 2/20 0.46
SRD5A2 P31213 1/20 0.46
LTB4R Q15722 1/20 0.46
LTB4R2 Q9NPC1 1/20 0.46
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
ALDH1A1 P00352 1/20 0.45
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3104540 0.81 NOX1 (0.50) MAOBNR4A1NR4A2NR4A3NOX1
SCHEMBL17890894 0.80 NOX1 (0.54) MAOBNR4A1NR4A2NR4A3NOX1
SCHEMBL191548 0.79 MAOB (0.50) MAOBNR4A1NR4A2NR4A3NOX1
SCHEMBL29633133 0.79 L3MBTL1 (0.37)
SCHEMBL8586195 0.79 ALDH1A1 (0.57) MAOBNR4A1NR4A2NR4A3NOX1
SCHEMBL29633179 0.79 MIF (0.40) KDM4EMEN1MAPTKMT2A
SCHEMBL7630006 0.78 ALOX5 (0.47) MAOBNR4A1NR4A2NR4A3NOX1
SCHEMBL2574961 0.77 ALDH1A1 (0.61) MAOBNR4A1NR4A2NR4A3NOX1
SCHEMBL192404 0.77 ALDH1A1 (0.49) MAOBNR4A1NR4A2NR4A3NOX1
SCHEMBL6779534 0.76 MAOB (0.65) MAOBNR4A1NR4A2NR4A3PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388542-A1 ANALOGUES OF PENTAMIDINE AND USES THEREFOR AURANSA INC. (US) 2025-12-25 US disclosed
US-20220144776-A1 ANALOGUES OF PENTAMIDINE AND USES THEREFOR AURANSA INC. 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388542-A1 ANALOGUES OF PENTAMIDINE AND USES THEREFOR MALT1, SLC38A7, SLC7A1 MAOB 4499/4885NR4A1 935/4885NR4A2 2329/4885
US-20220144776-A1 ANALOGUES OF PENTAMIDINE AND USES THEREFOR DPYD, TYMP, GOT1 MAOB 2853/4885NR4A1 3802/4885NR4A2 4204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.