Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1974217 | 1.00 | KIF11 (0.47) | KIF11TSHRGABRA1GABRB2CYP3A4 | |
| SCHEMBL5587823 | 0.81 | LMNA (0.50) | TSHRGABRA1GABRB2CYP3A4LMNA | |
| SCHEMBL5142961 | 0.80 | GABRA1 (0.56) | TSHRGABRA1GABRB2CYP3A4LMNA | |
| SCHEMBL30314538 | 0.80 | GABRA1 (0.56) | TSHRGABRA1GABRB2CYP3A4LMNA | |
| SCHEMBL15048534 | 0.79 | TRPA1 (0.46) | TSHRGABRA1GABRB2CYP3A4LMNA | |
| SCHEMBL21893895 | 0.78 | GABRA1 (0.60) | KIF11TSHRGABRA1GABRB2CYP3A4 | |
| SCHEMBL23705916 | 0.78 | GABRA1 (0.39) | TSHRGABRA1GABRB2CYP3A4LMNA | |
| Methoxymethane SCHEMBL10659099 | 0.77 | TSHR (0.59) | KIF11TSHRCYP3A4LMNAALDH1A1 | |
| SCHEMBL9321395 | 0.77 | GABRA1 (0.43) | TSHRGABRA1GABRB2CYP3A4LMNA | |
| SCHEMBL19204554 | 0.76 | ALOX15 (0.39) | KIF11TSHRGABRA1GABRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462597-A | Specific chemiluminescent probe for measuring CYP3A, preparation method and application thereof | 遵义医科大学 | 2025-02-18 | — | — | CN | claimed |
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |