Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099614 | 0.94 | OPRD1 (0.41) | CTSCALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29692448 | 0.92 | REN (0.39) | CTSCALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29789591 | 0.91 | CTSC (0.43) | CTSCALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29351243 | 0.91 | ALDH1A1 (0.44) | CTSCALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL13401853 | 0.91 | ALDH1A1 (0.44) | CTSCALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL30099537 | 0.87 | CTSB (0.42) | — | |
| SCHEMBL29364551 | 0.87 | CTSC (0.42) | CTSCALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL29566998 | 0.85 | ALDH1A1 (0.47) | CTSCALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL11656501 | 0.85 | ALDH1A1 (0.50) | CTSCALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL11656504 | 0.85 | ALDH1A1 (0.50) | CTSCALDH1A1LMNAMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115488-A1 | IMMUNOGENIC NANOVESICLES FOR CANCER IMMUNOTHERAPY | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-06-02 | — | — | WO | claimed |