Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788346 | 1.00 | ECE1 (0.55) | ECE1MUS81TOP2BSMN1; SMN2BLM | |
| SCHEMBL8788365 | 0.92 | ECE1 (0.53) | ECE1MUS81TOP2BSMN1; SMN2BLM | |
| SCHEMBL8788262 | 0.88 | ECE1 (0.54) | ECE1MUS81TOP2BSMN1; SMN2BLM | |
| SCHEMBL8788107 | 0.86 | ECE1 (0.56) | ECE1MUS81TOP2BSMN1; SMN2BLM | |
| SCHEMBL9197796 | 0.85 | TOP2B (0.46) | ECE1MUS81TOP2BSMN1; SMN2BLM | |
| SCHEMBL8791589 | 0.85 | ECE1 (0.57) | ECE1MUS81TOP2BSMN1; SMN2BLM | |
| Hydrochloric Acid SCHEMBL9200372 | 0.84 | TOP2B (0.46) | ECE1MUS81TOP2BSMN1; SMN2BLM | |
| SCHEMBL8788938 | 0.83 | ECE1 (0.57) | ECE1MUS81TOP2BSMN1; SMN2BLM | |
| SCHEMBL7557626 | 0.82 | MALT1 (0.62) | TOP2BSMN1; SMN2BLMMAPTMALT1 | |
| SCHEMBL31218590 | 0.82 | MALT1 (0.62) | TOP2BSMN1; SMN2BLMMAPTMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3226909-B1 | QUATERNARY AMINE COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH INC (US) | 2026-04-15 | — | — | EP | disclosed |
| US-20220304993-A1 | CONJUGATES OF AN ELECTRON-DONATING NITROGEN OR TERTIARY AMINE COMPRISING COMPOUNDS | ASCENDIS PHARMA A/S (DK) | 2022-09-29 | — | — | US | disclosed |
| EP-3986471-A1 | CONJUGATES OF AN ELECTRON-DONATING NITROGEN OR TERTIARY AMINE COMPRISING COMPOUNDS | Ascendis Pharma A/S (DK) | 2022-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220304993-A1 | CONJUGATES OF AN ELECTRON-DONATING NITROGEN OR TERTIARY AMINE COMPRISING COMPOUNDS | NQO1, HNMT, PNMT | ECE1 454/4885MUS81 2412/4885TOP2B 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.