Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876462 | 0.80 | MAOA (0.60) | ALDH1A1KDM4ENPC1RAB9AMAOA | |
| SCHEMBL14252988 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL7227151 | 0.80 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL29619913 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL2161251 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL30401424 | 0.78 | PTGS2 (0.69) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL29025501 | 0.78 | PTGS2 (0.69) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL20349925 | 0.77 | KDM4E (0.75) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL7228607 | 0.76 | KDM4E (0.68) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL20349955 | 0.75 | KDM4E (0.71) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115915972-A | Polygala tenuifolia extract for treating attention deficit hyperactivity disorder | 莱特先进生医股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114502011-A | Use of polygala root extract for treating severe melancholia | 莱特先进生医股份有限公司 | 2022-05-13 | — | — | CN | disclosed |