SCHEMBL2963698

SCHEMBL2963698

CN1CCN(c2ccc(CO)cc2)C(=O)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHKA P35790 1/20 0.44
VHL P40337 1/20 0.38
ELOC Q15369 1/20 0.38
ELOB Q15370 1/20 0.38
RAB9A P51151 2/20 0.36
S1PR1 P21453 1/20 0.36
DGAT1 O75907 1/20 0.34
PTGS2 P35354 2/20 0.33
BRD4 O60885 2/20 0.33
TYR P14679 1/20 0.33
DRD2 P14416 1/20 0.33
DRD3 P35462 1/20 0.33
BRD2 P25440 1/20 0.33
BRD3 Q15059 1/20 0.33
HTT P42858 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13201447 0.85 MGLL (0.44) RAB9AS1PR1MEN1NPC1KMT2A
SCHEMBL13201392 0.79 DRD2 (0.46) RAB9ADGAT1DRD2DRD3HTT
SCHEMBL21594891 0.75 CHKA (0.50) CHKAVHLELOCELOBRAB9A
SCHEMBL21594984 0.75 L3MBTL1 (0.52) CHKAVHLELOCELOBRAB9A
SCHEMBL2961616 0.75 ALDH1A1 (0.50) RAB9ATYRMEN1NPC1KMT2A
SCHEMBL3550353 0.71 DRD2 (0.50) CHKARAB9AS1PR1DGAT1DRD2
SCHEMBL3553583 0.70 S1PR1 (0.56) RAB9AS1PR1MEN1NPC1KMT2A
SCHEMBL24478670 0.69 MGLL (0.46) RAB9AS1PR1DRD2DRD3HRH3
SCHEMBL8149641 0.69 ALDH1A1 (0.57) MEN1KMT2AUSP2
SCHEMBL14473350 0.69 ALDH1A1 (0.62) RAB9AHTTMEN1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1445249-B1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO LTD (JP) 2012-11-07 EP disclosed
US-7772285-B2 Benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO., LTD. (JP) 2010-08-10 US disclosed
EP-1445249-A1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2004-08-11 EP disclosed