Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638404 | 0.83 | TYK2 (0.40) | TYK2CYP1A2MAPTABCG2ABCB1 | |
| SCHEMBL24557308 | 0.83 | TYK2 (0.40) | TYK2CYP1A2MAPTABCG2ABCB1 | |
| SCHEMBL29638411 | 0.78 | ALKBH5 (0.42) | CYP1A2MAPTXDHMEN1KMT2A | |
| SCHEMBL29638356 | 0.75 | TYK2 (0.38) | TYK2CYP1A2MAPTABCG2ABCB1 | |
| SCHEMBL29638357 | 0.74 | TYK2 (0.41) | TYK2CYP1A2MAPTABCG2ABCB1 | |
| SCHEMBL29638482 | 0.74 | TYK2 (0.35) | TYK2MAPTTP53ALDH1A1 | |
| SCHEMBL29638350 | 0.73 | PHGDH (0.36) | TYK2TP53 | |
| SCHEMBL29638310 | 0.73 | ALDH1A1 (0.40) | TYK2MAPTTP53ALDH1A1 | |
| SCHEMBL24557356 | 0.73 | PHGDH (0.36) | TYK2TP53 | |
| SCHEMBL24557288 | 0.72 | LYN (0.40) | CYP1A2MAPTMEN1KMT2AALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |