Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638323 | 0.78 | TYK2 (0.41) | ALKBH5XDHCYP1A2MAPTMEN1 | |
| SCHEMBL29638428 | 0.77 | CYP1A2 (0.44) | ALKBH5XDHCYP1A2MAPTMGLL | |
| SCHEMBL16423909 | 0.69 | KMT2A (0.49) | ALKBH5CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL29638406 | 0.67 | CYP1A2 (0.43) | ALKBH5CYP1A2MAPTMGLLMEN1 | |
| SCHEMBL30596268 | 0.64 | NPBWR1 (0.48) | CYP1A2MAPTMEN1RAB9AKMT2A | |
| SCHEMBL3262867 | 0.63 | ALKBH5 (0.54) | ALKBH5CYP1A2MAPTMGLLMEN1 | |
| SCHEMBL486408 | 0.63 | MAPT (0.71) | ALKBH5CYP1A2MAPTMGLLMEN1 | |
| SCHEMBL24557279 | 0.63 | MEN1 (0.42) | ALKBH5CYP1A2MAPTMEN1RAB9A | |
| SCHEMBL24557271 | 0.63 | SRC (0.46) | ALKBH5CYP1A2MAPTMEN1RAB9A | |
| SCHEMBL7656036 | 0.63 | ALKBH5 (0.50) | ALKBH5CYP1A2MAPTMGLLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |