Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638526 | 0.88 | PLK1 (0.40) | MAP3K14PDE10APLK1NPBWR1MCHR1 | |
| SCHEMBL29638355 | 0.86 | PLK1 (0.41) | MAP3K14PDE10APLK1NPBWR1MCHR1 | |
| SCHEMBL29638422 | 0.84 | ABHD16A (0.40) | CNR1ACHECNR2 | |
| SCHEMBL29638403 | 0.82 | MAP3K14 (0.36) | MAP3K14 | |
| SCHEMBL29638383 | 0.81 | RARG (0.36) | PDE10A | |
| SCHEMBL29638349 | 0.79 | PTGS2 (0.38) | — | |
| SCHEMBL29638375 | 0.79 | MAPK1 (0.32) | PDE10A | |
| SCHEMBL29638380 | 0.74 | PIK3CD (0.39) | PDE10APLK1NPBWR1MCHR1TSHR | |
| SCHEMBL30279785 | 0.68 | CYP3A4 (0.53) | ALOX5APFEN1TSHR | |
| SCHEMBL21055380 | 0.63 | DGAT1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |