Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638441 | 0.88 | MAP3K14 (0.35) | PLK1PDE10ANPBWR1MCHR1TSHR | |
| SCHEMBL29638355 | 0.86 | PLK1 (0.41) | PLK1PDE10ANPBWR1MCHR1PIK3CD | |
| SCHEMBL29638422 | 0.84 | ABHD16A (0.40) | MAPTHTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL29638403 | 0.82 | MAP3K14 (0.36) | MAPTRAB9ANPC1MAP3K14LMNA | |
| SCHEMBL29638380 | 0.82 | PIK3CD (0.39) | PLK1PDE10ANPBWR1MCHR1PIK3CD | |
| SCHEMBL29638383 | 0.81 | RARG (0.36) | PDE10APIK3CD | |
| SCHEMBL29638349 | 0.79 | PTGS2 (0.38) | PIK3CD | |
| SCHEMBL29638363 | 0.79 | PLK1 (0.41) | PLK1MAPTHTTRAB9ATSHR | |
| SCHEMBL29638375 | 0.79 | MAPK1 (0.32) | PDE10AMAPTALDH1A1KDM4E | |
| SCHEMBL30596266 | 0.68 | PDE4D (0.49) | NPBWR1MCHR1MAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |