Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638441 | 0.82 | MAP3K14 (0.35) | MAP3K14 | |
| SCHEMBL29638526 | 0.82 | PLK1 (0.40) | MAP3K14LMNAALDH1A1NPC1KDM4E | |
| SCHEMBL29638355 | 0.81 | PLK1 (0.41) | MAP3K14ALDH1A1KDM4EMAPT | |
| SCHEMBL29638422 | 0.80 | ABHD16A (0.40) | LMNAALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL29638349 | 0.76 | PTGS2 (0.38) | — | |
| SCHEMBL29638383 | 0.76 | RARG (0.36) | — | |
| SCHEMBL29638375 | 0.74 | MAPK1 (0.32) | ALDH1A1KDM4EMAPT | |
| SCHEMBL29638363 | 0.72 | PLK1 (0.41) | MAP3K14LMNAALDH1A1KDM4EMAPT | |
| SCHEMBL29638364 | 0.69 | PLK1 (0.41) | POLBALDH1A1NPC1RAB9AGAA | |
| SCHEMBL3581485 | 0.68 | KMT2A (0.42) | IDO1TDO2POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |