Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638381 | 0.82 | MAPK1 (0.33) | MAPK1MAPT | |
| SCHEMBL29638383 | 0.80 | RARG (0.36) | PDE10A | |
| SCHEMBL29638526 | 0.79 | PLK1 (0.40) | KDM4EALDH1A1MAPTPDE10A | |
| SCHEMBL29638441 | 0.79 | MAP3K14 (0.35) | PDE10A | |
| SCHEMBL29638349 | 0.78 | PTGS2 (0.38) | — | |
| SCHEMBL29638355 | 0.77 | PLK1 (0.41) | KDM4EALDH1A1MAPTPDE10A | |
| SCHEMBL29638422 | 0.75 | ABHD16A (0.40) | ALDH1A1MAPT | |
| SCHEMBL29638403 | 0.74 | MAP3K14 (0.36) | KDM4EALDH1A1MAPT | |
| SCHEMBL29638458 | 0.68 | MAPT (0.38) | MAPK1KDM4ENSD2ALDH1A1MAPT | |
| SCHEMBL23024892 | 0.62 | DGAT1 (0.35) | MAPTPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |