Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638383 | 0.89 | RARG (0.36) | PIK3CDRARGPDE10A | |
| SCHEMBL29638441 | 0.86 | MAP3K14 (0.35) | PLK1NPBWR1MCHR1MAP3K14TSHR | |
| SCHEMBL29638526 | 0.86 | PLK1 (0.40) | PLK1NPBWR1MCHR1MAP3K14PIK3CD | |
| SCHEMBL29638422 | 0.82 | ABHD16A (0.40) | MAPTALDH1A1HTT | |
| SCHEMBL29638403 | 0.81 | MAP3K14 (0.36) | MAP3K14MAPTKDM4EALDH1A1 | |
| SCHEMBL29638370 | 0.80 | PLK1 (0.44) | PLK1PIK3CDMAPTSLC2A1 | |
| SCHEMBL29638349 | 0.78 | PTGS2 (0.38) | PIK3CDRARG | |
| SCHEMBL29638375 | 0.77 | MAPK1 (0.32) | MAPTKDM4EALDH1A1PDE10A | |
| SCHEMBL29638380 | 0.69 | PIK3CD (0.39) | PLK1NPBWR1MCHR1PIK3CDMAPT | |
| SCHEMBL31166643 | 0.69 | TBXAS1 (0.47) | GABRG2GABRB3GABRA5GABRA3ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |