Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 6/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638415 | 0.84 | JAK2 (0.37) | PIK3CAPRKDCMTORTYK2 | |
| SCHEMBL24557251 | 0.84 | JAK2 (0.37) | PIK3CAPRKDCMTORTYK2 | |
| SCHEMBL29638471 | 0.82 | IDH1 (0.34) | PRKDCTYK2 | |
| SCHEMBL29638431 | 0.82 | PLK1 (0.41) | PRKDCTYK2PLK1 | |
| SCHEMBL24557311 | 0.82 | PLK1 (0.41) | PRKDCTYK2PLK1 | |
| SCHEMBL29638519 | 0.81 | TYK2 (0.45) | TYK2 | |
| SCHEMBL29638372 | 0.80 | TYK2 (0.42) | TYK2PLK1 | |
| SCHEMBL29638329 | 0.79 | FGFR4 (0.36) | TYK2KCNH2TNK2 | |
| SCHEMBL24557269 | 0.78 | TYK2 (0.40) | TYK2KCNH2SCN9A | |
| SCHEMBL29638376 | 0.78 | TYK2 (0.40) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |