Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445862 | 0.84 | DHFR (0.45) | IDO1DHFRRAB9AHDAC3HDAC1 | |
| SCHEMBL30402437 | 0.79 | IDO1 (0.40) | IDO1DHFRMAPK1HDAC3HDAC1 | |
| SCHEMBL24399749 | 0.79 | IDO1 (0.40) | IDO1DHFRMAPK1HDAC3HDAC1 | |
| SCHEMBL29638659 | 0.74 | PDE3A (0.44) | RAB9ASMN1; SMN2TDP1MAPTMAPK1 | |
| SCHEMBL18743102 | 0.68 | SMN1; SMN2 (0.37) | RAB9ASMN1; SMN2TDP1GAAMAPT | |
| SCHEMBL16865612 | 0.68 | SMN1; SMN2 (0.40) | IDO1DHFRNR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL12373439 | 0.67 | TRPA1 (0.51) | IDO1RAB9ACYP1A2 | |
| SCHEMBL29638488 | 0.67 | SYK (0.39) | HDAC3HDAC1HDAC6 | |
| SCHEMBL31674009 | 0.67 | ALDH1A1 (0.40) | IDO1RAB9ASMN1; SMN2TDP1GAA | |
| SCHEMBL15047854 | 0.66 | CYP1A2 (0.44) | TDP1GAAMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |