SCHEMBL29639702

SCHEMBL29639702

c1ccc2c(c1)CC(CN1CCN(c3ccc4c(c3)OCCO4)CC1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 1.00
DRD3 P35462 5/20 1.00
SIGMAR1 Q99720 3/20 1.00
HTR1A P08908 2/20 1.00
ADRA2A P08913 1/20 1.00
ADRA2C P18825 1/20 1.00
ADRA1D P25100 1/20 1.00
ADRA1A P35348 1/20 1.00
ADRA1B P35368 1/20 1.00
DRD4 P21917 4/20 0.52
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7810984 1.00 DRD2 (1.00) DRD2DRD3SIGMAR1HTR1AADRA2A
SCHEMBL6963642 0.92 SIGMAR1 (0.86) DRD2DRD3SIGMAR1HTR1AADRA2A
SCHEMBL7807312 0.92 HTR1A (0.84) DRD2DRD3SIGMAR1HTR1AADRA2A
SCHEMBL7810855 0.88 SIGMAR1 (0.78) DRD2DRD3SIGMAR1HTR1AADRA2A
SCHEMBL7805016 0.88 SIGMAR1 (0.78) DRD2DRD3SIGMAR1HTR1AADRA2A
SCHEMBL7805256 0.84 DRD2 (0.72) DRD2DRD3SIGMAR1HTR1AADRA2A
SCHEMBL7805320 0.83 SIGMAR1 (0.71) DRD2DRD3SIGMAR1HTR1AADRA2A
SCHEMBL7805322 0.83 DRD2 (0.71) DRD2DRD3SIGMAR1HTR1AADRA2A
SCHEMBL7805194 0.82 SIGMAR1 (0.70) DRD2DRD3SIGMAR1HTR1AADRA2A
SCHEMBL7812268 0.80 HTR1A (0.67) DRD2DRD3SIGMAR1HTR1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112575116-B Soybean whole genome SNP locus combination, gene chip and application 中国科学院东北地理与农业生态研究所 2023-05-12 CN claimed
US-20230381168-A1 ADJUNCTIVE THERAPY FOR DEPRESSION ANEUROTECH BV (BE) 2023-11-30 US disclosed
CN-112575116-B Soybean whole genome SNP locus combination, gene chip and application 中国科学院东北地理与农业生态研究所 2023-05-12 CN disclosed
US-20230091682-A1 COGNITIVE DISORDER PREVENTION AND THERAPY ANEUROTECH BV (BE) 2023-03-23 US disclosed
EP-4087552-A1 COGNITIVE DISORDER PREVENTION AND THERAPY Aneurotech IP BV (BE) 2022-11-16 EP disclosed
CN-115279356-A Prevention and treatment of cognitive disorders 安尤罗泰克IP私人有限公司 2022-11-01 CN disclosed
US-20220205053-A1 Combination of Soybean Whole Genome SNP Loci, Gene Chip and Application Thereof NORTHEAST INSTITUTE OF GEOGRAPHY AND AGROECOLOGY,CHINESE ACADEMY OF SCIENCES (CN) 2022-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230091682-A1 COGNITIVE DISORDER PREVENTION AND THERAPY HTR2A, HTR1A, HTR2C DRD2 7/4885DRD3 14/4885SIGMAR1 272/4885
US-20230381168-A1 ADJUNCTIVE THERAPY FOR DEPRESSION HTR2A, HTR3B, HTR5A DRD2 11/4885DRD3 26/4885SIGMAR1 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.