Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 8/20 | 0.42 |
| ▸ | JUN | P05412 | 4/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.42 |
| ▸ | RELA | Q04206 | 4/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ATF1 | P18846 | 4/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933717 | 0.82 | JUN (0.41) | NFKB1JUNNFKB2RELASORT1 | |
| SCHEMBL29693635 | 0.70 | KDM4E (0.37) | NFKB1SORT1KDM4EMAPTATF1 | |
| SCHEMBL6936291 | 0.70 | KDM4E (0.55) | KDM4E | |
| SCHEMBL11017429 | 0.70 | KDM4E (0.37) | NFKB1SORT1KDM4EMAPTATF1 | |
| SCHEMBL23328199 | 0.69 | KDM4E (0.36) | KDM4E | |
| Formamide SCHEMBL21678847 | 0.68 | KDM4E (0.37) | KDM4E | |
| Ammonia Solution, Strong SCHEMBL29084542 | 0.67 | KDM4E (0.35) | KDM4E | |
| SCHEMBL8396932 | 0.67 | KDM4E (0.70) | NFKB1JUNNFKB2RELAKDM4E | |
| SCHEMBL12203584 | 0.66 | NFKB1 (0.44) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL23631774 | 0.66 | KIF11 (0.37) | KDM4EGAAKIF11ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502543-A | Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof | 拜欧斯瑞克斯公司 | 2022-05-13 | — | — | CN | disclosed |