Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 8/20 | 0.35 |
| ▸ | CES2 | O00748 | 7/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702560 | 0.84 | PARP10 (0.45) | LMNACA1CA2 | |
| SCHEMBL15956227 | 0.78 | TP53 (0.52) | RXRACYP26A1CYP26B1CA12CA1 | |
| SCHEMBL18291832 | 0.78 | MAPK1 (0.45) | LMNA | |
| SCHEMBL22712558 | 0.76 | LMNA (0.46) | LMNA | |
| SCHEMBL15956007 | 0.73 | CA1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12973676 | 0.73 | HSD17B1 (0.53) | LMNA | |
| SCHEMBL14744167 | 0.73 | PARP1 (0.44) | CA1CA2 | |
| SCHEMBL12123651 | 0.72 | ALDH1A1 (0.40) | RXRA | |
| SCHEMBL21581921 | 0.71 | NOS3 (0.37) | LMNAPDE2ACA1CA2 | |
| SCHEMBL12356799 | 0.71 | RXRA (0.49) | RXRACYP26A1CYP26B1RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502543-A | Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof | 拜欧斯瑞克斯公司 | 2022-05-13 | — | — | CN | disclosed |