Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29604926 | 1.00 | CYP19A1 (0.51) | CYP19A1CES1ACHESIGMAR1DRD2 | |
| SCHEMBL2592601 | 0.89 | MAOA (0.50) | CYP19A1CES1ACHESIGMAR1DRD2 | |
| SCHEMBL1332811 | 0.82 | CYP19A1 (0.53) | CYP19A1CES1ACHESIGMAR1DRD2 | |
| SCHEMBL13039620 | 0.79 | DRD2 (0.56) | CYP19A1CES1ACHESIGMAR1DRD2 | |
| SCHEMBL296403 | 0.79 | ACHE (0.59) | CYP19A1CES1ACHEKDM4EMAPT | |
| SCHEMBL29752636 | 0.79 | ACHE (0.59) | CYP19A1CES1ACHEKDM4EMAPT | |
| SCHEMBL15624255 | 0.78 | ACHE (0.49) | CYP19A1CES1ACHESIGMAR1DRD2 | |
| SCHEMBL11819054 | 0.78 | CYP19A1 (0.53) | CYP19A1CES1ACHESIGMAR1DRD2 | |
| SCHEMBL1094690 | 0.78 | CYP19A1 (0.53) | CYP19A1CES1ACHESIGMAR1DRD2 | |
| SCHEMBL30707960 | 0.78 | CYP19A1 (0.53) | CYP19A1CES1ACHESIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038581-A1 | A ONE STEP SYNTHESIS OF 2-SUBSTITUTED BENZO[B]THIOPHENES | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IIT Madras) (IN) | 2021-03-04 | — | — | WO | claimed |
| CN-109293672-B | 3, 4-dihydro-1H-spiro [ naphthalene-2, 1' -thienochromene ] derivative and synthesis method and application thereof | 浙江师范大学 | 2021-02-19 | — | — | CN | claimed |
| CN-104591988-A | Method for synthesizing 6-bromo-2-tetralone | GANSU RES INST OF CHEMICAL INDUSTRY | 2015-05-06 | — | — | CN | claimed |
| US-6897231-B2 | Indazole derivatives as JNK inhibitors and compositions and methods related thereto | SIGNAL PHARMACEUTICALS, INC. (US) | 2005-05-24 | — | — | US | claimed |
| EP-0125695-B1 | 2-BROMO-1-TETRALONE DERIVATIVES | KIRIN BEER KABUSHIKI KAISHA (JP) | 1987-07-22 | — | — | EP | claimed |
| EP-0125695-A2 | 2-Bromo-1-tetralone derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1984-11-21 | — | — | EP | claimed |
| JP-59210039-A | — | — | None | — | — | JP | disclosed |
| JP-59163317-A | — | — | None | — | — | JP | disclosed |
| US-20240018146-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | MITOKININ, INC. (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018146-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | MITOKININ, INC. (US) | 2024-01-18 | — | — | US | disclosed |
| CN-117142938-A | Method for preparing 1, 4-naphthoquinone compound by selectively oxidizing aromatic ketone | 大连理工大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-116023200-B | Method for preparing methylene compound by reduction of aromatic aldehyde (ketone) compound | 江西扬帆新材料有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116023200-A | Method for preparing methylene compound by reduction of aromatic aldehyde (ketone) compound | 浙江扬帆新材料股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| US-4174397-A | TREATMENT OF OBESITY AND LIPID METABOLISM DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | disclosed |
| US-3985731-A | MICROBIOCIDES, MOTOR ACTIVITY INDUCERS, CNS STIMULANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3970650-A | DRUG INTERMEDIATE | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1976-07-20 | — | — | US | disclosed |
| US-3970650-A | DRUG INTERMEDIATE | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1976-07-20 | — | — | US | disclosed |
| US-3959308-A | Substituted naphtho pyrazoles | SANDOZ, INC. (US) | 1976-05-25 | — | — | US | disclosed |
| US-3954983-A | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS | RICHARDSON-MERRELL INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3932430-A | Substituted indeno, naphtho and cyclohepta pyrazoles | SANDOZ, INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018146-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | PINK1, NME4, AK2 | CYP19A1 4264/4885CES1 1914/4885ACHE 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.