Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783785 | 1.00 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL25437165 | 0.86 | THRB (0.49) | L3MBTL1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL25436022 | 0.86 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL25436402 | 0.84 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL3218011 | 0.84 | KMT2A (0.57) | L3MBTL1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL31724375 | 0.82 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL30930824 | 0.81 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL30930821 | 0.81 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL8663801 | 0.81 | HDAC1 (0.49) | L3MBTL1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL16883651 | 0.80 | TBXAS1 (0.47) | L3MBTL1ALDH1A1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450006-A | TrkB positive allosteric modulators | 斯特拉斯堡大学 | 2022-05-06 | — | — | CN | disclosed |