Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | FABP4 | P15090 | 8/20 | 0.72 |
| ▸ | PTGIR | P43119 | 8/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.45 |
| ▸ | FABP3 | P05413 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674739 | 1.00 | KDM4E (1.00) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19163857 | 0.92 | KDM4E (0.85) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9428515 | 0.90 | MEN1 (0.82) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9593239 | 0.89 | ALDH1A1 (0.80) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9428853 | 0.86 | KDM4E (0.76) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8066970 | 0.85 | FABP4 (0.79) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14698129 | 0.85 | KDM4E (0.74) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9594904 | 0.84 | KDM4E (0.72) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9428317 | 0.84 | FABP4 (1.00) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30398835 | 0.84 | FABP4 (1.00) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250205518-A1 | PULMONARY HYPERTENSION TREATMENT | SONIVIE LTD. (IL) | 2025-06-26 | — | — | US | disclosed |
| US-12251582-B2 | Pulmonary hypertension treatment | SONIVIE LTD. (IL) | 2025-03-18 | — | — | US | disclosed |
| US-20240100018-A1 | COMPOUNDS FOR THE TREATMENT OF A DISEASE OR DISORDER, METHODS FOR IDENTIFYING SAID COMPOUNDS | CEDARS-SINAI MEDICAL CENTER | 2024-03-28 | — | — | US | disclosed |
| CN-116211904-B | Donggui extract and its extraction method and application | 广州青岚生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116211904-A | Donggui extract and its extraction method and application | 广州青岚生物科技有限公司 | 2023-06-06 | — | — | CN | disclosed |
| US-20220241617-A1 | PULMONARY HYPERTENSION TREATMENT | SONIVIE LTD. (IL) | 2022-08-04 | — | — | US | disclosed |
| US-20220244263-A1 | METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-08-04 | — | — | US | disclosed |
| US-11318331-B2 | Pulmonary hypertension treatment | SONIVIE LTD. (IL) | 2022-05-03 | — | — | US | disclosed |