Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | HPGD | P15428 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.80 |
| ▸ | FABP4 | P15090 | 8/20 | 0.57 |
| ▸ | PTGIR | P43119 | 4/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.38 |
| ▸ | FABP3 | P05413 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640642 | 0.89 | KDM4E (1.00) | ALDH1A1HPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL674739 | 0.89 | KDM4E (1.00) | ALDH1A1HPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL9593730 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL19163857 | 0.81 | KDM4E (0.85) | ALDH1A1HPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL9428515 | 0.79 | MEN1 (0.82) | ALDH1A1HPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL9452943 | 0.77 | FABP4 (0.49) | ALDH1A1HPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL9261099 | 0.76 | LMNA (0.53) | ALDH1A1HPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL9428853 | 0.76 | KDM4E (0.76) | ALDH1A1HPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL8066970 | 0.75 | FABP4 (0.79) | ALDH1A1HPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL14698129 | 0.75 | KDM4E (0.74) | ALDH1A1HPGDKDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254576-A | Diphenyl-heterocyclic-oxazole as platelet aggregation inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-10-19 | — | — | US | claimed |
| US-5254576-A | Diphenyl-heterocyclic-oxazole as platelet aggregation inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-10-19 | — | — | US | disclosed |