Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645580 | 0.90 | P2RX7 (0.36) | P2RX7THRBRXFP1KDM4EALDH1A1 | |
| SCHEMBL29645588 | 0.88 | MAPT (0.43) | P2RX7USP1WDR48THRBRXFP1 | |
| SCHEMBL29646008 | 0.84 | KDM4E (0.47) | THRBRXFP1KDM4EALDH1A1POLB | |
| SCHEMBL29645803 | 0.83 | POLB (0.46) | P2RX7THRBRXFP1KDM4EALDH1A1 | |
| SCHEMBL29645431 | 0.81 | SLC40A1 (0.35) | P2RX7USP1WDR48POLB | |
| SCHEMBL29645960 | 0.81 | P2RX7 (0.33) | P2RX7MAPT | |
| SCHEMBL22980060 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL22988389 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL29645642 | 0.78 | MAPT (0.43) | P2RX7THRBRXFP1KDM4EPOLB | |
| SCHEMBL29645475 | 0.77 | KDM4E (0.44) | THRBRXFP1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |