Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645682 | 0.92 | ADORA3 (0.40) | NR1H2NR1H3ADORA3ADORA2AADORA1 | |
| SCHEMBL31149976 | 0.91 | ADORA3 (0.38) | NR1H2NR1H3ADORA3ADORA2AADORA1 | |
| SCHEMBL29645803 | 0.90 | POLB (0.46) | ADORA3ADORA2AADORA1MAPTP2RX7 | |
| SCHEMBL29646148 | 0.87 | LMNA (0.39) | MAPT | |
| SCHEMBL29645755 | 0.86 | MAPT (0.40) | ADORA3ADORA2AADORA1MAPTXDH | |
| SCHEMBL29645837 | 0.85 | EGFR (0.36) | P2RX7XDH | |
| SCHEMBL29645723 | 0.85 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL29645738 | 0.84 | NTRK1 (0.36) | ADORA3ADORA2AADORA1P2RX7 | |
| SCHEMBL29645600 | 0.84 | PDK2 (0.32) | ADORA3ADORA2AADORA1P2RX7 | |
| SCHEMBL29645888 | 0.83 | MAPT (0.55) | ADORA3ADORA2AADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |