Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645724 | 0.90 | AXL (0.34) | EGFRKDM1AALKJUNMAPK8 | |
| SCHEMBL29646166 | 0.90 | PIK3CD (0.35) | EGFRKDM1AMAPK8MAPK10MET | |
| SCHEMBL29646031 | 0.87 | KDR (0.33) | EGFRADORA3METCLK2 | |
| SCHEMBL29645782 | 0.86 | MAPT (0.43) | KDM1AADORA3ALK | |
| SCHEMBL29645810 | 0.86 | ADORA3 (0.35) | KDM1AADORA3ALKMETIRAK4 | |
| SCHEMBL29645704 | 0.84 | MAPT (0.37) | ADORA3 | |
| SCHEMBL29645835 | 0.83 | ADORA3 (0.39) | EGFRADORA3ALKJUNMAPK8 | |
| SCHEMBL29645991 | 0.83 | MAPT (0.44) | ADORA3 | |
| SCHEMBL29645787 | 0.82 | MAPT (0.38) | — | |
| SCHEMBL29645548 | 0.82 | ADORA3 (0.37) | HDAC8ADORA3ALKMETWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |