Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645787 | 0.91 | MAPT (0.38) | MAPTTP53RXFP1POLB | |
| SCHEMBL31149887 | 0.90 | RXFP1 (0.36) | MAPTADORA3ADORA1ABCG2ADORA2A | |
| SCHEMBL29645521 | 0.89 | ADORA3 (0.43) | MAPTADORA3ADORA1ADORA2ATP53 | |
| SCHEMBL29645991 | 0.88 | MAPT (0.44) | MAPTADORA3ADORA1ADORA2AXDH | |
| SCHEMBL29646027 | 0.87 | MAPT (0.36) | MAPTADORA3ADORA1ADORA2ATP53 | |
| SCHEMBL29645503 | 0.85 | ADORA3 (0.49) | MAPTADORA3ADORA1ADORA2ATP53 | |
| SCHEMBL29645825 | 0.85 | TP53 (0.41) | MAPTADORA3ADORA1ABCG2ADORA2A | |
| SCHEMBL29645501 | 0.84 | EGFR (0.33) | ADORA3 | |
| SCHEMBL29645764 | 0.82 | ADORA3 (0.43) | MAPTADORA3ADORA1ADORA2ATP53 | |
| SCHEMBL31149874 | 0.81 | MAPT (0.36) | MAPTABCG2TP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |