Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645521 | 0.91 | ADORA3 (0.43) | ADORA3MAPTADORA2AADORA1THRB | |
| SCHEMBL31149957 | 0.90 | MAPT (0.40) | ADORA3MAPTADORA2AADORA1THRB | |
| SCHEMBL29645787 | 0.89 | MAPT (0.38) | MAPTCSNK1DPDE10ATP53RXFP1 | |
| SCHEMBL29645499 | 0.88 | MAPT (0.37) | MAPTCSNK1DPDE10ATP53RXFP1 | |
| SCHEMBL29645458 | 0.87 | MAPT (0.50) | ADORA3MAPTADORA1THRBTP53 | |
| SCHEMBL29645744 | 0.86 | MAPT (0.36) | MAPTCYP1A2CYP3A4CSNK1DPDE10A | |
| SCHEMBL29645778 | 0.85 | LMNA (0.38) | MAPTTHRBMEN1KMT2ATP53 | |
| SCHEMBL29645468 | 0.83 | MAPT (0.44) | ADORA3MAPTADORA2AADORA1THRB | |
| SCHEMBL31149881 | 0.81 | MAPT (0.40) | ADORA3MAPTADORA2AADORA1THRB | |
| SCHEMBL31149874 | 0.80 | MAPT (0.36) | MAPTTHRBUSP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |