Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646027 | 0.91 | MAPT (0.36) | MAPTPDE10ATP53LMNA | |
| SCHEMBL31149879 | 0.91 | MAPT (0.35) | MAPTCSNK1DMAT2AKCNT1SCN9A | |
| SCHEMBL29645787 | 0.88 | MAPT (0.38) | MAPTCSNK1DPDE10ATP53LMNA | |
| SCHEMBL29645511 | 0.88 | ADORA3 (0.41) | MAPTCSNK1DPDE10ATP53LMNA | |
| SCHEMBL29646148 | 0.86 | LMNA (0.39) | MAPTCSNK1DMAT2AKCNT1SCN9A | |
| SCHEMBL29645458 | 0.85 | MAPT (0.50) | MAPTTP53POLBRXFP1 | |
| SCHEMBL29645744 | 0.84 | MAPT (0.36) | MAPTCSNK1DMAT2APDE10ATP53 | |
| SCHEMBL29646050 | 0.84 | MAPT (0.42) | MAPTPOLBRXFP1PSEN1PSEN2 | |
| SCHEMBL29646031 | 0.84 | KDR (0.33) | KCNT1SCN9APDE10APSEN1PSEN2 | |
| SCHEMBL31150040 | 0.82 | MAPT (0.35) | MAPTPDE10ATP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |