Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645914 | 0.92 | NR1H2 (0.40) | ADORA3ADORA1NR1H2NR1H3ADORA2A | |
| SCHEMBL29646148 | 0.91 | LMNA (0.39) | MAPTTP53RXFP1 | |
| SCHEMBL29645803 | 0.90 | POLB (0.46) | ADORA3ADORA1ADORA2AMAPTTP53 | |
| SCHEMBL31149962 | 0.90 | ADORA3 (0.39) | ADORA3ADORA1NR1H2NR1H3ADORA2A | |
| SCHEMBL29645618 | 0.89 | ADORA3 (0.40) | ADORA3ADORA1ADORA2AMAPTTP53 | |
| SCHEMBL29645933 | 0.87 | TP53 (0.41) | ADORA3ADORA1ADORA2AMAPTTP53 | |
| SCHEMBL29645825 | 0.87 | TP53 (0.41) | ADORA3ADORA1ADORA2AMAPTTP53 | |
| SCHEMBL29645837 | 0.86 | EGFR (0.36) | TP53P2RX7XDHSMN1; SMN2RXFP1 | |
| SCHEMBL29646027 | 0.85 | MAPT (0.36) | ADORA3ADORA1NR1H2NR1H3ADORA2A | |
| SCHEMBL29645738 | 0.85 | NTRK1 (0.36) | ADORA3ADORA1ADORA2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |