Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645499 | 0.91 | MAPT (0.37) | MAPTLMNAPDE10ATP53 | |
| SCHEMBL31150040 | 0.90 | MAPT (0.35) | MAPTP2RX7MEN1CYP1A2CYP3A4 | |
| SCHEMBL29646050 | 0.90 | MAPT (0.42) | MAPTP2RX7MEN1KMT2AADORA3 | |
| SCHEMBL29645521 | 0.87 | ADORA3 (0.43) | MAPTADORA3ADORA1ADORA2ALMNA | |
| SCHEMBL29645704 | 0.87 | MAPT (0.37) | MAPTADORA3ADORA1ADORA2ATP53 | |
| SCHEMBL29645682 | 0.85 | ADORA3 (0.40) | MAPTP2RX7ADORA3ADORA1ADORA2A | |
| SCHEMBL29646031 | 0.85 | KDR (0.33) | P2RX7ADORA3ADORA1ADORA2APDE10A | |
| SCHEMBL29645503 | 0.84 | ADORA3 (0.49) | MAPTKMT2AADORA3ADORA1ADORA2A | |
| SCHEMBL31149879 | 0.82 | MAPT (0.35) | MAPTCYP1A2CYP3A4CYP2C19PDE10A | |
| SCHEMBL29645909 | 0.81 | ADORA3 (0.44) | MAPTADORA3ADORA1ADORA2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |