Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645682 | 0.91 | ADORA3 (0.40) | MAPTTP53RXFP1 | |
| SCHEMBL31149906 | 0.91 | MAPT (0.37) | LMNAMAPTTP53RXFP1MAT2A | |
| SCHEMBL29645502 | 0.89 | RXFP1 (0.41) | LMNAMAPTTP53RXFP1CSNK1D | |
| SCHEMBL29645799 | 0.88 | LMNA (0.38) | LMNAMAPTTP53RXFP1CSNK1D | |
| SCHEMBL29645778 | 0.88 | LMNA (0.38) | LMNAMAPTTP53RXFP1THRB | |
| SCHEMBL29645914 | 0.87 | NR1H2 (0.40) | MAPT | |
| SCHEMBL29645499 | 0.86 | MAPT (0.37) | LMNAMAPTTP53RXFP1MAT2A | |
| SCHEMBL29645458 | 0.85 | MAPT (0.50) | MAPTTP53RXFP1THRB | |
| SCHEMBL29645803 | 0.85 | POLB (0.46) | MAPTTP53RXFP1THRB | |
| SCHEMBL29645837 | 0.84 | EGFR (0.36) | TP53RXFP1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |