Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | TTK | P33981 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645922 | 0.93 | ADORA3 (0.42) | MAPTTHRBRXFP1ADORA3TP53 | |
| SCHEMBL29645650 | 0.89 | MAPT (0.50) | MAPTTHRBRXFP1ADORA3TP53 | |
| SCHEMBL29645835 | 0.88 | ADORA3 (0.39) | MAPTRXFP1ADORA3POLBALDH1A1 | |
| SCHEMBL29645782 | 0.88 | MAPT (0.43) | MAPTTHRBRXFP1ADORA3TP53 | |
| SCHEMBL29645664 | 0.86 | ADORA3 (0.40) | ADORA3TTKMETAURKB | |
| SCHEMBL29646322 | 0.84 | RXFP1 (0.40) | MAPTTHRBRXFP1ADORA3TP53 | |
| SCHEMBL29645874 | 0.83 | ADORA3 (0.40) | MAPTADORA3MET | |
| SCHEMBL29645783 | 0.83 | ADORA3 (0.42) | ADORA3 | |
| SCHEMBL29646074 | 0.83 | MAPT (0.48) | MAPTTHRBRXFP1ADORA3SMN1; SMN2 | |
| SCHEMBL29645943 | 0.82 | MAPT (0.50) | MAPTTHRBRXFP1ADORA3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |