Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 8/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | FECH | P22830 | 1/20 | 0.36 |
| ▸ | MST1R | Q04912 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646322 | 0.90 | RXFP1 (0.40) | ADORA3ADORA1ADORA2AMAPTALK | |
| SCHEMBL29645783 | 0.90 | ADORA3 (0.42) | ADORA3ADORA2B | |
| SCHEMBL29645782 | 0.89 | MAPT (0.43) | ADORA3ADORA1ADORA2AMAPTALK | |
| SCHEMBL29646053 | 0.89 | ADORA3 (0.41) | ADORA3ADORA1ADORA2AALKMET | |
| SCHEMBL29645922 | 0.88 | ADORA3 (0.42) | ADORA3MAPT | |
| SCHEMBL29645764 | 0.87 | ADORA3 (0.43) | ADORA3ADORA1ADORA2AMAPT | |
| SCHEMBL29645835 | 0.84 | ADORA3 (0.39) | ADORA3ADORA1ADORA2AMAPTALK | |
| SCHEMBL29645664 | 0.84 | ADORA3 (0.40) | ADORA3ADORA1ADORA2AALKMET | |
| SCHEMBL29646046 | 0.83 | ADORA1 (0.36) | ADORA3ADORA1ADORA2AMETKDM1A | |
| SCHEMBL29645988 | 0.83 | MAPT (0.47) | ADORA3ADORA1ADORA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |