Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645783 | 0.90 | ADORA3 (0.42) | ADORA3 | |
| SCHEMBL29645874 | 0.90 | ADORA3 (0.40) | ADORA3ADORA2AADORA1MAPTALK | |
| SCHEMBL29645782 | 0.90 | MAPT (0.43) | RXFP1TP53THRBADORA3ADORA2A | |
| SCHEMBL29645922 | 0.89 | ADORA3 (0.42) | RXFP1TP53THRBADORA3MAPT | |
| SCHEMBL29646053 | 0.88 | ADORA3 (0.41) | ADORA3ADORA2AADORA1ALK | |
| SCHEMBL29645835 | 0.85 | ADORA3 (0.39) | RXFP1ADORA3ADORA2AADORA1MAPT | |
| SCHEMBL29645842 | 0.85 | MET (0.33) | RXFP1TP53THRBADORA3ADORA2A | |
| SCHEMBL29645919 | 0.84 | MAPT (0.41) | RXFP1TP53THRBADORA3MAPT | |
| SCHEMBL29646002 | 0.83 | MAPT (0.48) | RXFP1TP53THRBADORA3ADORA2A | |
| SCHEMBL29645724 | 0.83 | AXL (0.34) | ALKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |