Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | FECH | P22830 | 1/20 | 0.31 |
| ▸ | MST1R | Q04912 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645724 | 0.87 | AXL (0.34) | EGFRMETWNT1DYRK1AAXL | |
| SCHEMBL29646166 | 0.84 | PIK3CD (0.35) | EGFRMET | |
| SCHEMBL29645842 | 0.83 | MET (0.33) | EGFRPRKDCMET | |
| SCHEMBL29645501 | 0.82 | EGFR (0.33) | EGFRMETHDAC8WNT1DYRK1A | |
| SCHEMBL29646031 | 0.82 | KDR (0.33) | EGFRMETMERTK | |
| SCHEMBL29645782 | 0.81 | MAPT (0.43) | — | |
| SCHEMBL29646322 | 0.81 | RXFP1 (0.40) | EGFR | |
| SCHEMBL29645874 | 0.80 | ADORA3 (0.40) | METCYP3A4CYP2D6CYP2C9FECH | |
| SCHEMBL29645783 | 0.78 | ADORA3 (0.42) | — | |
| SCHEMBL29646053 | 0.78 | ADORA3 (0.41) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |