SCHEMBL2964849

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2970978	0.90	PDK2 (0.39)	HSD11B1NOTUMPDK2ALDH1A1CYP3A4
	SCHEMBL2975651	0.86	HSD11B1 (0.37)	HSD11B1NOTUMPDK2ALDH1A1CYP3A4
	SCHEMBL18242471	0.79	PDK2 (0.30)	PDK2
	SCHEMBL197671	0.78	HSD11B1 (0.56)	HSD11B1NOTUMALDH1A1CYP3A4CYP2D6
	SCHEMBL2963747	0.78	HSD11B1 (0.36)	HSD11B1NOTUMALDH1A1CYP2C19HPGD
	SCHEMBL6649115	0.77	HSD11B1 (0.38)	HSD11B1NOTUMPDK2ALDH1A1CYP3A4
	SCHEMBL18241988	0.77	—	—
	Hydrochloric Acid SCHEMBL29010139	0.76	HSD11B1 (0.54)	HSD11B1NOTUMALDH1A1CYP3A4CYP2D6
	SCHEMBL8022901	0.76	HSD11B1 (0.54)	HSD11B1NOTUMALDH1A1CYP3A4CYP2D6
	SCHEMBL18242355	0.75	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.