Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307784 | 0.90 | HCAR3 (0.52) | FGFR1PLA2G4AHCAR3PTGER4HPGD | |
| SCHEMBL29738122 | 0.82 | FGFR1 (0.55) | FGFR1PLA2G4AHCAR3TBXA2RF2 | |
| SCHEMBL3838757 | 0.80 | FGFR1 (0.56) | FGFR1PLA2G4AHCAR3TBXA2RF2 | |
| SCHEMBL30497305 | 0.80 | MTNR1A (0.51) | FGFR1PLA2G4AHCAR3TBXA2RF2 | |
| SCHEMBL29556127 | 0.80 | MEN1 (0.56) | FGFR1PLA2G4AHCAR3TBXA2RMTNR1A | |
| SCHEMBL26672356 | 0.80 | MEN1 (0.56) | FGFR1PLA2G4AHCAR3TBXA2RMTNR1A | |
| SCHEMBL2936871 | 0.78 | PLA2G4A (0.49) | FGFR1PLA2G4AHCAR3TBXA2RMTNR1A | |
| SCHEMBL29649186 | 0.77 | FGFR1 (0.50) | FGFR1PLA2G4AHCAR3TBXA2RF2 | |
| SCHEMBL30269205 | 0.77 | FGFR1 (0.47) | FGFR1PLA2G4AHCAR3TBXA2RF2 | |
| SCHEMBL1528672 | 0.77 | POLB (0.54) | FGFR1PLA2G4AHCAR3TBXA2RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335374-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-11-11 | — | — | CN | disclosed |