Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30448515 | 0.89 | L3MBTL1 (0.55) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL31681497 | 0.81 | SPHK1 (0.45) | ALDH1A1CYP3A4CYP2C9LTA4H | |
| SCHEMBL29649451 | 0.81 | SPHK1 (0.45) | ALDH1A1CYP3A4CYP2C9LTA4H | |
| SCHEMBL29649606 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL25364561 | 0.81 | SIRT1 (0.41) | ALDH1A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL25364554 | 0.81 | SIRT1 (0.41) | ALDH1A1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL29601869 | 0.79 | KIF11 (0.45) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL15822487 | 0.76 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL26242790 | 0.76 | KIF11 (0.46) | ALDH1A1HDAC3HDAC6KMT2AKDM4E | |
| SCHEMBL25359570 | 0.76 | SSTR3 (0.41) | CYP3A4CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237008-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | Elucida Oncology, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093800-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. (US) | 2022-05-05 | — | — | WO | disclosed |