SCHEMBL2965041

SCHEMBL2965041

Cc1c(-c2cccc3ccccc23)cc2c(c1Br)C=CC2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
HTR7 P34969 3/20 0.33
HTR1A P08908 2/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CYP2A6 P11509 2/20 0.32
ALDH1A1 P00352 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DHFR P00374 1/20 0.31
ALOX5 P09917 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALPL P05186 1/20 0.31
GAA P10253 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2959125 0.89 MAOA (0.33) MAOAMAOBHTR7HTR1ACA12
SCHEMBL2970494 0.83 CD274 (0.32) DHFR
SCHEMBL2960634 0.82 MAOA (0.30) MAOAMAOB
SCHEMBL2960740 0.80 HTR1A (0.33) HTR7HTR1AALDH1A1MAPTSMN1; SMN2
SCHEMBL2961422 0.80 DHFR (0.36) MAOAMAOBCA12CA1CA2
SCHEMBL2970904 0.79 KDM4E (0.36) MAOAMAOBHTR7HTR1AALDH1A1
SCHEMBL2958171 0.79 SQOR (0.33) ALDH1A1
SCHEMBL2974077 0.76 CA12 (0.34) MAOAMAOBHTR7HTR1ACA12
SCHEMBL2960039 0.76 ALDH1A1 (0.36) MAOAMAOBHTR7HTR1ACA12
SCHEMBL2975589 0.76 ALDH1A1 (0.36) MAOAMAOBHTR7HTR1ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 MAOA 958/4885MAOB 902/4885HTR7 2417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.