SCHEMBL29652527

SCHEMBL29652527

CCc1ccc(OC)c(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2noc3cc(-c4cnn(C)c4)ccc23)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MET P08581 2/20 0.37
▸ BRD4 O60885 1/20 0.37
▸ PTGDR2 Q9Y5Y4 1/20 0.37
▸ KAT7 O95251 4/20 0.37
▸ KAT6A Q92794 4/20 0.37
▸ KAT6B Q8WYB5 2/20 0.36
▸ POLB P06746 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ ALPL P05186 1/20 0.35
▸ MAPT P10636 4/20 0.34
▸ KDR P35968 2/20 0.34
▸ TP53 P04637 1/20 0.34
▸ FGFR3 P22607 1/20 0.34
▸ CSF1R P07333 2/20 0.34
▸ PDGFRB P09619 1/20 0.34
▸ KAT5 Q92993 1/20 0.34
▸ KAT8 Q9H7Z6 1/20 0.34
▸ NTRK1 P04629 1/20 0.34
▸ NTRK3 Q16288 1/20 0.34
▸ NTRK2 Q16620 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21641940 1.00 MET (0.37) METBRD4PTGDR2KAT7KAT6A
SCHEMBL29652370 0.88 KAT7 (0.41) BRD4KAT7KAT6AKAT6BPOLB
SCHEMBL21596863 0.86 KDM4E (0.36) PTGDR2KAT7KAT6AKAT6BPOLB
SCHEMBL31605635 0.86 KDM4E (0.36) PTGDR2KAT7KAT6AKAT6BPOLB
SCHEMBL29652474 0.85 BRD4 (0.38) BRD4KAT7KAT6AKAT6BPOLB
SCHEMBL28514884 0.85 BRD4 (0.38) BRD4KAT7KAT6AKAT6BPOLB
SCHEMBL29652373 0.84 TSHR (0.39) BRD4KAT7KAT6AKAT6BPOLB
SCHEMBL31605548 0.80 MAPT (0.37) BRD4KAT7KAT6AKAT6BPOLB
SCHEMBL21596794 0.80 MAPT (0.37) BRD4KAT7KAT6AKAT6BPOLB
SCHEMBL31605563 0.79 KAT7 (0.36) BRD4KAT7KAT6AKAT6BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 — — CN disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 — — EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 MET 3843/4885BRD4 1909/4885PTGDR2 2756/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B MET 59/4885BRD4 343/4885PTGDR2 2678/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 MET 3840/4885BRD4 1913/4885PTGDR2 2756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback