Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635375 | 0.81 | KDM4E (0.34) | PTGER4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20635504 | 0.81 | TP53 (0.34) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL20635376 | 0.74 | GAA (0.33) | PTGER4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29654030 | 0.74 | RORC (0.42) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28797832 | 0.74 | RORC (0.42) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL20635537 | 0.71 | RORC (0.53) | KDM4EALDH1A1 | |
| SCHEMBL20635378 | 0.71 | NPC1 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL15543439 | 0.70 | SCN9A (0.41) | — | |
| SCHEMBL17179792 | 0.68 | CTNNB1 (0.43) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL25934717 | 0.68 | MMP2 (0.35) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952298-B | Indole carboxamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-09-03 | — | — | CN | disclosed |
| US-20200131123-A1 | INDOLE-FORMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131123-A1 | INDOLE-FORMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | TPH1, TPH2, PAH | PTGER4 1421/4885PARP1 2375/4885PARP2 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.