Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 4/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.38 |
| ▸ | TK2 | O00142 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655349 | 0.94 | SLC5A1 (0.41) | LGALS8SLC5A1PTPN1SLC28A3HPGD | |
| SCHEMBL29655360 | 0.94 | SLC5A1 (0.41) | LGALS8SLC5A1PTPN1SLC28A3HPGD | |
| SCHEMBL29655308 | 0.90 | PRKCA (0.42) | LGALS8SLC5A1PTPN1SLC28A3HSD17B10 | |
| SCHEMBL29655356 | 0.86 | PRKCA (0.38) | SLC5A1PTPN1 | |
| SCHEMBL29655336 | 0.76 | PRKCA (0.42) | PTPN1HSD17B10CYP3A4 | |
| SCHEMBL13075407 | 0.66 | SLC5A2 (0.51) | SLC5A1SLC28A3SLC5A2NPC1RAB9A | |
| SCHEMBL16687903 | 0.65 | LGALS8 (0.48) | LGALS8PTPN1HSD17B10THRBLGALS3 | |
| SCHEMBL970383 | 0.65 | LGALS8 (0.54) | LGALS8PTPN1KDM4EMAPTLGALS3 | |
| SCHEMBL12917696 | 0.65 | LGALS8 (0.54) | LGALS8PTPN1KDM4EMAPTLGALS3 | |
| SCHEMBL970381 | 0.65 | LGALS8 (0.54) | LGALS8PTPN1KDM4EMAPTLGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | LGALS8 1144/4885SLC5A1 31/4885PTPN1 3282/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | LGALS8 1144/4885SLC5A1 31/4885PTPN1 3282/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | LGALS8 1144/4885SLC5A1 31/4885PTPN1 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.