Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18614818 | 0.84 | EGFR (0.49) | EGFRAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL3679414 | 0.80 | AGTR1 (0.51) | EGFRAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL28246406 | 0.80 | EGFR (0.63) | EGFRAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL784606 | 0.76 | POLB (0.49) | EGFRAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL5189056 | 0.74 | KMT2A (0.40) | EGFRALDH1A1KDM4EPOLBGLA | |
| SCHEMBL29655556 | 0.74 | KMT2A (0.40) | EGFRALDH1A1KDM4EPOLBGLA | |
| SCHEMBL28322929 | 0.71 | AGTR1 (0.50) | AGTR1ALDH1A1KDM4EHPGDPOLB | |
| Butyric Acid SCHEMBL9251503 | 0.70 | FABP4 (0.45) | EGFRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11959493 | 0.70 | GPR3 (0.55) | ALDH1A1KDM4EPOLBMEN1CYP1A2 | |
| SCHEMBL9851534 | 0.69 | ATM (0.42) | ALDH1A1KDM4EHPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166940-A1 | QUINUCLIDINE COMPOUNDS FOR MODULATING ALPHA7 -NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | Alpharmagen, LLC (US) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016007630-A1 | QUINUCLIDINE COMPOUNDS FOR MODULATING ALPHA7 -NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | ALPHARMAGEN, LLC (US) | 2016-01-14 | — | — | WO | disclosed |